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Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene Transfer
Gene therapy for cystic fibrosis using non-viral, plasmid-based formulations has been the subject of intensive research for over two decades but a clinically viable product has yet to materialise in large part due to inefficient transgene expression. Minicircle DNA give enhanced and more persistent...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4792149/ https://ncbi.nlm.nih.gov/pubmed/26975732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23125 |
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