Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model

بواسطة Alzubi, Jamal, Pallant, Celeste, Mussolino, Claudio, Howe, Steven J., Thrasher, Adrian J., Cathomen, Toni
الحاوية / القاعدة Sci Rep (2017)

Tolerance Induction Using Lentiviral Gene Delivery Delays Onset and Severity of Collagen II Arthritis

بواسطة Gjertsson, Inger, Laurie, Karen L, Devitt, James, Howe, Steven J, Thrasher, Adrian J, Holmdahl, Rikard, Gustafsson, Kenth
منشور في 2009

Inhibition of Mitochondrial Complex I Impairs Release of α-Galactosidase by Jurkat Cells

بواسطة Lambert, Jonathan R. A., Howe, Steven J., Rahim, Ahad A., Burke, Derek G., Heales, Simon J. R.
الحاوية / القاعدة Int J Mol Sci (2019)

Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene Transfer

بواسطة Munye, Mustafa M., Tagalakis, Aristides D., Barnes, Josephine L., Brown, Rachel E., McAnulty, Robin J., Howe, Steven J., Hart, Stephen L.
الحاوية / القاعدة Sci Rep (2016)

Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cel...

بواسطة Zhang, Fang, Thornhill, Susannah I., Howe, Steven J., Ulaganathan, Meera, Schambach, Axel, Sinclair, Joanna, Kinnon, Christine, Gaspar, H. Bobby, Antoniou, Michael, Thrasher, Adrian J.
منشور في 2007

Perinatal Gene Transfer to the Liver

بواسطة McKay, Tristan R, Rahim, Ahad A, Buckley, Suzanne M.K, Ward, Natalie J, Chan, Jerry K.Y, Howe, Steven J, Waddington, Simon N
منشور في 2011

Evidence for Contribution of CD4+CD25+ Regulatory T Cells in Maintaining Immune Tolerance to Human Factor IX following Perinatal Adenovirus Vector Delivery

بواسطة Nivsarkar, Megha S., Buckley, Suzanne M. K., Parker, Alan L., Perocheau, Dany, McKay, Tristan R., Rahim, Ahad A., Howe, Steven J., Waddington, Simon N.
الحاوية / القاعدة J Immunol Res (2015)

Gene Delivery of a Mutant TGFβ3 Reduces Markers of Scar Tissue Formation After Cutaneous Wounding

بواسطة Waddington, Simon N, Crossley, Rachel, Sheard, Vicky, Howe, Steven J, Buckley, Suzanne MK, Coughlan, Lynda, Gilham, David E, Hawkins, Robert E, McKay, Tristan R
منشور في 2010

The Landscape of Early Clinical Gene Therapies outside of Oncology

بواسطة Rittié, Laure, Athanasopoulos, Takis, Calero-Garcia, Miguel, Davies, Marie L., Dow, David J., Howe, Steven J., Morrison, Alastair, Ricciardelli, Ida, Saudemont, Aurore, Jespers, Laurent, Clay, Timothy M.
الحاوية / القاعدة Mol Ther (2019)

Lentiviral vectors can be used for full-length dystrophin gene therapy

بواسطة Counsell, John R., Asgarian, Zeinab, Meng, Jinhong, Ferrer, Veronica, Vink, Conrad A., Howe, Steven J., Waddington, Simon N., Thrasher, Adrian J., Muntoni, Francesco, Morgan, Jennifer E., Danos, Olivier
الحاوية / القاعدة Sci Rep (2017)

Lentiviral vectors can be used for full-length dystrophin gene therapy

بواسطة Counsell, John R., Asgarian, Zeinab, Meng, Jinhong, Ferrer, Veronica, Vink, Conrad A., Howe, Steven J., Waddington, Simon N., Thrasher, Adrian J., Muntoni, Francesco, Morgan, Jennifer E., Danos, Olivier
الحاوية / القاعدة Sci Rep (2017)

Erratum: Lentiviral vectors can be used for full-length dystrophin gene therapy

بواسطة Counsell, John R., Asgarian, Zeinab, Meng, Jinhong, Ferrer, Veronica, Vink, Conrad A., Howe, Steven J., Waddington, Simon N., Thrasher, Adrian J., Muntoni, Francesco, Morgan, Jennifer E., Danos, Olivier
الحاوية / القاعدة Sci Rep (2017)

Self-inactivating Gammaretroviral Vectors for Gene Therapy of X-linked Severe Combined Immunodeficiency

بواسطة Thornhill, Susannah I, Schambach, Axel, Howe, Steven J, Ulaganathan, Meera, Grassman, Elke, Williams, David, Schiedlmeier, Bernhard, Sebire, Neil J, Gaspar, H Bobby, Kinnon, Christine, Baum, Christopher, Thrasher, Adrian J
الحاوية / القاعدة Mol Ther (2008)

BMI-1 extends proliferative potential of human bronchial epithelial cells while retaining their mucociliary differentiation capacity

بواسطة Munye, Mustafa M., Shoemark, Amelia, Hirst, Robert A., Delhove, Juliette M., Sharp, Tyson V., McKay, Tristan R., O’Callaghan, Christopher, Baines, Deborah L., Howe, Steven J., Hart, Stephen L.
الحاوية / القاعدة Am J Physiol Lung Cell Mol Physiol (2017)

Enhancement of mouse hematopoietic stem/progenitor cell function via transient gene delivery using integration-deficient lentiviral vectors

بواسطة Alonso-Ferrero, Maria E., van Til, Niek P., Bartolovic, Kerol, Mata, Márcia F., Wagemaker, Gerard, Moulding, Dale, Williams, David A., Kinnon, Christine, Waddington, Simon N., Milsom, Michael D., Howe, Steven J.
الحاوية / القاعدة Exp Hematol (2018)

Systemic gene delivery following intravenous administration of AAV9 to fetal and neonatal mice and late-gestation nonhuman primates

بواسطة Mattar, Citra N., Wong, Andrew M. S., Hoefer, Klemens, Alonso-Ferrero, Maria E., Buckley, Suzanne M. K., Howe, Steven J., Cooper, Jonathan D., Waddington, Simon N., Chan, Jerry K. Y., Rahim, Ahad A.
الحاوية / القاعدة FASEB J (2015)

Eliminating HIV-1 Packaging Sequences from Lentiviral Vector Proviruses Enhances Safety and Expedites Gene Transfer for Gene Therapy

بواسطة Vink, Conrad A., Counsell, John R., Perocheau, Dany P., Karda, Rajvinder, Buckley, Suzanne M.K., Brugman, Martijn H., Galla, Melanie, Schambach, Axel, McKay, Tristan R., Waddington, Simon N., Howe, Steven J.
الحاوية / القاعدة Mol Ther (2017)

Hematopoietic Stem Cell and Gene Therapy Corrects Primary Neuropathology and Behavior in Mucopolysaccharidosis IIIA Mice

بواسطة Langford-Smith, Alexander, Wilkinson, Fiona L, Langford-Smith, Kia J, Holley, Rebecca J, Sergijenko, Ana, Howe, Steven J, Bennett, William R, Jones, Simon A, Wraith, JE, Merry, Catherine LR, Wynn, Robert F, Bigger, Brian W
منشور في 2012

In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters

بواسطة Buckley, Suzanne M. K., Delhove, Juliette M. K. M., Perocheau, Dany P., Karda, Rajvinder, Rahim, Ahad A., Howe, Steven J., Ward, Natalie J., Birrell, Mark A., Belvisi, Maria G., Arbuthnot, Patrick, Johnson, Mark R., Waddington, Simon N., McKay, Tristan R.
الحاوية / القاعدة Sci Rep (2015)

Lentiviral Vector Integration Profiles Differ in Rodent Postmitotic Tissues

بواسطة Bartholomae, Cynthia C, Arens, Anne, Balaggan, Kamaljit S, Yáñez-Muñoz, Rafael J, Montini, Eugenio, Howe, Steven J, Paruzynski, Anna, Korn, Bernhard, Appelt, Jens Uwe, MacNeil, Angus, Cesana, Daniela, Abel, Ulrich, Glimm, Hanno, Naldini, Luigi, Ali, Robin R, Thrasher, Adrian J, von Kalle, Christof, Schmidt, Manfred
منشور في 2011