The Rheumatoid Arthritis HLA-DRB1 Shared Epitope

door Holoshitz, Joseph
Gepubliceerd in 2010

The Quest for Better Understanding of HLA-Disease Association: Scenes from a Road Less Travelled By

door Holoshitz, Joseph
Gepubliceerd in 2013

A reciprocal HLA-Disease Association in Rheumatoid Arthritis and Pemphigus Vulgaris

door van Drongelen, Vincent, Holoshitz, Joseph
Gepubliceerd in Front Biosci (Landmark Ed) (2017)

HLA-Disease Associations in Rheumatoid Arthritis

door van Drongelen, Vincent, Holoshitz, Joseph
Gepubliceerd in Rheum Dis Clin North Am (2017)

MHC molecules in health and disease: At the cusp of a paradigm shift

door de Almeida, Denise E, Holoshitz, Joseph
Gepubliceerd in 2011

A role for calreticulin in the pathogenesis of rheumatoid arthritis

door Holoshitz, Joseph, De Almeida, Denise E., Ling, Song
Gepubliceerd in 2010

New Insights into the Functional Role of the Rheumatoid Arthritis Shared Epitope

door de Almeida, Denise E., Ling, Song, Holoshitz, Joseph
Gepubliceerd in 2011

Uncovering a Shared Epitope–Activated Protein Citrullination Pathway

door van Drongelen, Vincent, Ali, Wahida H., Holoshitz, Joseph
Gepubliceerd in J Immunol (2020)

Identification of the Rheumatoid Arthritis Shared Epitope Binding Site on Calreticulin

door Ling, Song, Cheng, Andrew, Pumpens, Paul, Michalak, Marek, Holoshitz, Joseph
Gepubliceerd in 2010

Gender-biased regulation of human IL-17-producing cells in vitro by peptides corresponding to distinct HLA-DRB1 allele-coded sequences

door Blanco, Luz P., Plegue, Melissa, Fung-Leung, Wai-Ping, Holoshitz, Joseph
Gepubliceerd in J Immune Based Ther Vaccines Antimicrob (2013)

The rheumatoid arthritis shared epitope increases cellular susceptibility to oxidative stress by antagonizing an adenosine-mediated anti-oxidative pathway

door Ling, Song, Li, Zhanguo, Borschukova, Olga, Xiao, Liqun, Pumpens, Paul, Holoshitz, Joseph
Gepubliceerd in 2007

Citrullinated calreticulin potentiates rheumatoid arthritis shared epitope signaling

door Ling, Song, Cline, Erika N, Haug, Timothy S, Fox, David A, Holoshitz, Joseph
Gepubliceerd in 2013

Shared Epitope Antagonistic Ligands - A New Therapeutic Strategy in Mice with Erosive Arthritis

door Ling, Song, Liu, Ying, Fu, Jiaqi, Colletta, Alessandro, Gilon, Chaim, Holoshitz, Joseph
Gepubliceerd in Arthritis Rheumatol (2015)

Developing Potent Backbone Cyclic Peptides Bearing the Shared Epitope Sequence as Rheumatoid Arthritis Drug-Leads

door Naveh, Shirly, Tal-Gan, Yftah, Ling, Song, Hoffman, Amnon, Holoshitz, Joseph, Gilon, Chaim
Gepubliceerd in 2011

Spontaneous destructive periodontitis and skeletal bone damage in transgenic mice carrying a human shared epitope-coding HLA-DRB1 allele

door Gehlot, Prashasnika, Volk, Sarah L, Rios, Hector F, Jepsen, Karl J, Holoshitz, Joseph
Gepubliceerd in RMD Open (2016)

IMMUNE DYSREGULATION BY THE RHEUMATOID ARTHRITIS SHARED EPITOPE

door De Almeida, Denise E., Ling, Song, Pi, Xiujun, Hartmann-Scruggs, Anne M., Pumpens, Paul, Holoshitz, Joseph
Gepubliceerd in 2010

HLA-DRB1 allelic epitopes that associate with autoimmune disease risk or protection activate reciprocal macrophage polarization

door van Drongelen, Vincent, Scavuzzi, Bruna Miglioranza, Nogueira, Sarah Veloso, Miller, Frederick W., Sawalha, Amr H., Holoshitz, Joseph
Gepubliceerd in Sci Rep (2021)

A Small Shared Epitope-Mimetic Compound Potently Accelerates Osteoclast-Mediated Bone Damage in Autoimmune Arthritis

door Fu, Jiaqi, Ling, Song, Liu, Ying, Yang, Jianyi, Naveh, Shirly, Hannah, Margaret, Gilon, Chaim, Zhang, Yang, Holoshitz, Joseph
Gepubliceerd in 2013

An HLA-DRB1-Coded Signal Transduction Ligand Facilitates Inflammatory Arthritis. A New Mechanism of Autoimmunity

door Holoshitz, Joseph, Liu, Ying, Fu, Jiaqi, Joseph, Jeena, Ling, Song, Colletta, Alessandro, Sharma, Prannda, Begun, Dana, Goldstein, Steven, Taichman, Russell
Gepubliceerd in 2012

Shared epitope–aryl hydrocarbon receptor crosstalk underlies the mechanism of gene–environment interaction in autoimmune arthritis

door Fu, Jiaqi, Nogueira, Sarah V., van Drongelen, Vincent, Coit, Patrick, Ling, Song, Rosloniec, Edward F., Sawalha, Amr H., Holoshitz, Joseph
Gepubliceerd in Proc Natl Acad Sci U S A (2018)