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New Insights into the Functional Role of the Rheumatoid Arthritis Shared Epitope

The shared epitope (SE) - an HLA-DRB1-encoded 5-amino acid sequence motif carried by the vast majority of rheumatoid arthritis (RA) patients - is a risk factor for severe disease. The mechanistic basis of RA-SE association is unknown. This group has previously demonstrated that the SE acts as a sign...

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Detalhes bibliográficos
Main Authors: de Almeida, Denise E., Ling, Song, Holoshitz, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153557/
https://ncbi.nlm.nih.gov/pubmed/21420962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.03.035
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