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IMMUNE DYSREGULATION BY THE RHEUMATOID ARTHRITIS SHARED EPITOPE
Rheumatoid arthritis (RA) is closely associated with HLA-DRB1 alleles that code a five-amino acid sequence motif in positions 70–74 of the HLA-DRβ chain, called the shared epitope (SE). The mechanistic basis of SE-RA association is unknown. We have recently found that the SE functions as an allele-s...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3111926/ https://ncbi.nlm.nih.gov/pubmed/20592276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904002 |
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