The Rheumatoid Arthritis HLA-DRB1 Shared Epitope

Por Holoshitz, Joseph
Publicado em 2010

The Quest for Better Understanding of HLA-Disease Association: Scenes from a Road Less Travelled By

Por Holoshitz, Joseph
Publicado em 2013

A reciprocal HLA-Disease Association in Rheumatoid Arthritis and Pemphigus Vulgaris

Por van Drongelen, Vincent, Holoshitz, Joseph
Publicado no Front Biosci (Landmark Ed) (2017)

HLA-Disease Associations in Rheumatoid Arthritis

Por van Drongelen, Vincent, Holoshitz, Joseph
Publicado no Rheum Dis Clin North Am (2017)

MHC molecules in health and disease: At the cusp of a paradigm shift

Por de Almeida, Denise E, Holoshitz, Joseph
Publicado em 2011

A role for calreticulin in the pathogenesis of rheumatoid arthritis

Por Holoshitz, Joseph, De Almeida, Denise E., Ling, Song
Publicado em 2010

New Insights into the Functional Role of the Rheumatoid Arthritis Shared Epitope

Por de Almeida, Denise E., Ling, Song, Holoshitz, Joseph
Publicado em 2011

Uncovering a Shared Epitope–Activated Protein Citrullination Pathway

Por van Drongelen, Vincent, Ali, Wahida H., Holoshitz, Joseph
Publicado no J Immunol (2020)

Identification of the Rheumatoid Arthritis Shared Epitope Binding Site on Calreticulin

Por Ling, Song, Cheng, Andrew, Pumpens, Paul, Michalak, Marek, Holoshitz, Joseph
Publicado em 2010

Gender-biased regulation of human IL-17-producing cells in vitro by peptides corresponding to distinct HLA-DRB1 allele-coded sequences

Por Blanco, Luz P., Plegue, Melissa, Fung-Leung, Wai-Ping, Holoshitz, Joseph
Publicado no J Immune Based Ther Vaccines Antimicrob (2013)

The rheumatoid arthritis shared epitope increases cellular susceptibility to oxidative stress by antagonizing an adenosine-mediated anti-oxidative pathway

Por Ling, Song, Li, Zhanguo, Borschukova, Olga, Xiao, Liqun, Pumpens, Paul, Holoshitz, Joseph
Publicado em 2007

Citrullinated calreticulin potentiates rheumatoid arthritis shared epitope signaling

Por Ling, Song, Cline, Erika N, Haug, Timothy S, Fox, David A, Holoshitz, Joseph
Publicado em 2013

Shared Epitope Antagonistic Ligands - A New Therapeutic Strategy in Mice with Erosive Arthritis

Por Ling, Song, Liu, Ying, Fu, Jiaqi, Colletta, Alessandro, Gilon, Chaim, Holoshitz, Joseph
Publicado no Arthritis Rheumatol (2015)

Developing Potent Backbone Cyclic Peptides Bearing the Shared Epitope Sequence as Rheumatoid Arthritis Drug-Leads

Por Naveh, Shirly, Tal-Gan, Yftah, Ling, Song, Hoffman, Amnon, Holoshitz, Joseph, Gilon, Chaim
Publicado em 2011

Spontaneous destructive periodontitis and skeletal bone damage in transgenic mice carrying a human shared epitope-coding HLA-DRB1 allele

Por Gehlot, Prashasnika, Volk, Sarah L, Rios, Hector F, Jepsen, Karl J, Holoshitz, Joseph
Publicado no RMD Open (2016)

IMMUNE DYSREGULATION BY THE RHEUMATOID ARTHRITIS SHARED EPITOPE

Por De Almeida, Denise E., Ling, Song, Pi, Xiujun, Hartmann-Scruggs, Anne M., Pumpens, Paul, Holoshitz, Joseph
Publicado em 2010

HLA-DRB1 allelic epitopes that associate with autoimmune disease risk or protection activate reciprocal macrophage polarization

Por van Drongelen, Vincent, Scavuzzi, Bruna Miglioranza, Nogueira, Sarah Veloso, Miller, Frederick W., Sawalha, Amr H., Holoshitz, Joseph
Publicado no Sci Rep (2021)

A Small Shared Epitope-Mimetic Compound Potently Accelerates Osteoclast-Mediated Bone Damage in Autoimmune Arthritis

Por Fu, Jiaqi, Ling, Song, Liu, Ying, Yang, Jianyi, Naveh, Shirly, Hannah, Margaret, Gilon, Chaim, Zhang, Yang, Holoshitz, Joseph
Publicado em 2013

An HLA-DRB1-Coded Signal Transduction Ligand Facilitates Inflammatory Arthritis. A New Mechanism of Autoimmunity

Por Holoshitz, Joseph, Liu, Ying, Fu, Jiaqi, Joseph, Jeena, Ling, Song, Colletta, Alessandro, Sharma, Prannda, Begun, Dana, Goldstein, Steven, Taichman, Russell
Publicado em 2012

Shared epitope–aryl hydrocarbon receptor crosstalk underlies the mechanism of gene–environment interaction in autoimmune arthritis

Por Fu, Jiaqi, Nogueira, Sarah V., van Drongelen, Vincent, Coit, Patrick, Ling, Song, Rosloniec, Edward F., Sawalha, Amr H., Holoshitz, Joseph
Publicado no Proc Natl Acad Sci U S A (2018)