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HLA-Disease Associations in Rheumatoid Arthritis

The etiology and pathogenesis of rheumatoid arthritis (RA) are influenced by environmental and genetic risk factors. Shared epitope-coding HLA-DRB1 alleles increase RA risk and severity; however, the underlying mechanisms of action remain unclear. In contrast, several other DRB1 alleles protect agai...

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Detalhes bibliográficos
Publicado no:Rheum Dis Clin North Am
Main Authors: van Drongelen, Vincent, Holoshitz, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643023/
https://ncbi.nlm.nih.gov/pubmed/28711139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.rdc.2017.04.003
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