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HLA-Disease Associations in Rheumatoid Arthritis
The etiology and pathogenesis of rheumatoid arthritis (RA) are influenced by environmental and genetic risk factors. Shared epitope-coding HLA-DRB1 alleles increase RA risk and severity; however, the underlying mechanisms of action remain unclear. In contrast, several other DRB1 alleles protect agai...
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| Published in: | Rheum Dis Clin North Am |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5643023/ https://ncbi.nlm.nih.gov/pubmed/28711139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.rdc.2017.04.003 |
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