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Association of MHC and rheumatoid arthritis:HLA polymorphisms in phenotypic variants of rheumatoid arthritis

Genes in the human leukocyte antigen (HLA) region remain the most powerful disease risk genes in rheumatoid arthritis (RA). Several allelic variants of HLA-DRB1 genes have been associated with RA, supporting a role for T-cell receptor-HLA-antigen interactions in the pathologic process. Disease-assoc...

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Bibliographic Details
Main Authors: Weyand, Cornelia M, Goronzy, Jörg J
Format: Artigo
Language:Inglês
Published: BioMed Central 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC130005/
https://ncbi.nlm.nih.gov/pubmed/11094432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar90
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