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Association of MHC and rheumatoid arthritis:HLA polymorphisms in phenotypic variants of rheumatoid arthritis

Genes in the human leukocyte antigen (HLA) region remain the most powerful disease risk genes in rheumatoid arthritis (RA). Several allelic variants of HLA-DRB1 genes have been associated with RA, supporting a role for T-cell receptor-HLA-antigen interactions in the pathologic process. Disease-assoc...

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Main Authors: Weyand, Cornelia M, Goronzy, Jörg J
格式: Artigo
語言:Inglês
出版: BioMed Central 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC130005/
https://ncbi.nlm.nih.gov/pubmed/11094432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar90
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