A carregar...

Shared epitope–aryl hydrocarbon receptor crosstalk underlies the mechanism of gene–environment interaction in autoimmune arthritis

The susceptibility to autoimmune diseases is affected by genetic and environmental factors. In rheumatoid arthritis (RA), the shared epitope (SE), a five-amino acid sequence motif encoded by RA-associated HLA-DRB1 alleles, is the single most significant genetic risk factor. The risk conferred by the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fu, Jiaqi, Nogueira, Sarah V., van Drongelen, Vincent, Coit, Patrick, Ling, Song, Rosloniec, Edward F., Sawalha, Amr H., Holoshitz, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939100/
https://ncbi.nlm.nih.gov/pubmed/29666259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722124115
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!