Fatty Acid Allosteric Regulation of C-H Activation in Plant and Animal Lipoxygenases

door Offenbacher, Adam R., Holman, Theodore R.
Gepubliceerd in Molecules (2020)

SUBSTRATE SPECIFICITY EFFECTS OF LIPOXYGENASE PRODUCTS AND INHIBITORS ON SOYBEAN LIPOXYGENASE-1

door Wecksler, Aaron T., Garcia, Natalie K., Holman, Theodore R.
Gepubliceerd in 2009

PSEUDOPEROXIDASE INVESTIGATIONS OF HYDROPEROXIDES AND INHIBITORS WITH HUMAN LIPOXYGENASES

door Hoobler, Eric K., Holz, Charles, Holman, Theodore R.
Gepubliceerd in 2013

A HIGH THROUGHPUT MASS SPECTROMETRIC ASSAY FOR DISCOVERY OF HUMAN LIPOXYGENASE INHIBITORS AND ALLOSTERIC EFFECTORS

door Jameson, J. Brian, Kenyon, Victor, Holman, Theodore R.
Gepubliceerd in Anal Biochem (2015)

The potential of 12/15-lipoxygenase inhibitors in stroke therapy

door van Leyen, Klaus, Holman, Theodore R, Maloney, David J
Gepubliceerd in Future Med Chem (2014)

Substrate Specificity Changes for Human Reticulocyte and Epithelial 15-Lipoxygenases Reveal Allosteric Product Regulation

door Wecksler, Aaron T., Kenyon, Victor, Deschamps, Joshua D., Holman, Theodore R.
Gepubliceerd in 2008

INHIBITORY AND MECHANISTIC INVESTIGATIONS OF OXO-LIPIDS WITH HUMAN LIPOXYGENASE ISOZYMES

door Armstrong, Michelle M., Diaz, Giovanni, Kenyon, Victor, Holman, Theodore R.
Gepubliceerd in 2014

Differential Contribution of Lipoxygenase Isozymes to Nigrostriatal Vulnerability

door Chou, Vivian P., Holman, Theodore R., Manning-Bog, Amy B.
Gepubliceerd in Neuroscience (2012)

Mechanistic Investigations of Human Reticulocyte 15- and Platelet 12-Lipoxygenases with Arachidonic Acid

door Wecksler, Aaron T., Jacquot, Cyril, van der Donk, Wilfred A., Holman, Theodore R.
Gepubliceerd in 2009

Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease

door Chou, Vivian P., Ko, Novie, Holman, Theodore R., Manning-Boğ, Amy B.
Gepubliceerd in 2014

Kinetic and Spectroscopic Studies of N694C Lipoxygenase: A Probe of the Substrate Activation Mechanism of a Non-Heme Ferric Enzyme

door Neidig, Michael L., Wecksler, Aaron T., Schenk, Gerhard, Holman, Theodore R., Solomon, Edward I.
Gepubliceerd in 2007

ATP Allosterically Activates the Human 5-Lipoxygenase Molecular Mechanism of Arachidonic Acid and 5(S)-Hydroperoxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic Acid

door Smyrniotis, Christopher J., Barbour, Shannon R., Xia, Zexin, Hixon, Mark S., Holman, Theodore R.
Gepubliceerd in 2014

Structure Activity Relationship Studies of Flavonoids as Potent Inhibitors of Human Platelet 12-hLO, Reticulocyte 15-hLO-1 and Prostate Epithelial 15-hLO-2

door Vasquez-Martinez, Yesseny, Ohri, Rachana V., Kenyon, Victor, Holman, Theodore R., Sepúlveda-Boza, Silvia
Gepubliceerd in 2007

KINETIC AND STRUCTURAL INVESTIGATIONS INTO THE ALLOSTERIC AND PH EFFECT ON SUBSTRATE SPECIFICITY OF HUMAN EPITHELIAL 15-LIPOXYGENASE-2

door Joshi, Netra, Hoobler, Eric K., Perry, Steven, Diaz, Giovanni, Fox, Brian, Holman, Theodore R.
Gepubliceerd in 2013

Contributions of 12/15-Lipoxygenase to bleeding in the brain following ischemic stroke

door Zheng, Yi, Liu, Yu, Karatas, Hulya, Yigitkanli, Kazim, Holman, Theodore R., van Leyen, Klaus
Gepubliceerd in Adv Exp Med Biol (2019)

Strict Regiospecificity of Human Epithelial 15-Lipoxygenase-2 Delineates Its Transcellular Synthesis Potential

door Green, Abigail R., Barbour, Shannon, Horn, Thomas, Carlos, Jose, Raskatov, Jevgenij A., Holman, Theodore R.
Gepubliceerd in Biochemistry (2016)

Synthesis of 11-Thialinoleic Acid and 14-Thialinoleic Acid, Inhibitors of Soybean and Human Lipoxygenases

door Jacquot, Cyril, McGinley, Chris M., Plata, Erik, Holman, Theodore R., van der Donk, Wilfred A.
Gepubliceerd in 2008

Investigations of human platelet-type 12-lipoxygenase: role of lipoxygenase products in platelet activation(1)

door Ikei, Kenneth N., Yeung, Jennifer, Apopa, Patrick L., Ceja, Jesús, Vesci, Joanne, Holman, Theodore R., Holinstat, Michael
Gepubliceerd in 2012

Minireview: 12-Lipoxygenase and Islet β-Cell Dysfunction in Diabetes

door Tersey, Sarah A., Bolanis, Esther, Holman, Theodore R., Maloney, David J., Nadler, Jerry L., Mirmira, Raghavendra G.
Gepubliceerd in Mol Endocrinol (2015)

5S,15S-Dihydroperoxyeicosatetraenoic acid (5,15-diHpETE) as a Lipoxin Intermediate: Reactivity and Kinetics with Human Leukocyte 5-Lipoxygenase, Platelet 12-Lipoxygenase, and Retic...

door Green, Abigail R., Freedman, Cody, Tena, Jennyfer, Tourdot, Benjamin E., Liu, Benjamin, Holinstat, Michael, Holman, Theodore R.
Gepubliceerd in Biochemistry (2018)