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5S,15S-Dihydroperoxyeicosatetraenoic acid (5,15-diHpETE) as a Lipoxin Intermediate: Reactivity and Kinetics with Human Leukocyte 5-Lipoxygenase, Platelet 12-Lipoxygenase, and Reticulocyte 15-Lipoxygenase-1

The reaction of 5,15-diHpETE with human 5-lipoxygenase (LOX), human platelet 12-LOX and human reticulocyte 15-LOX-1 was investigated to determine the reactivity and relative rates of producing lipoxins (LXs). 5-LOX does not react with 5,15-diHpETE, although it can produce LXA(4) when 15-HpETE is the...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Green, Abigail R., Freedman, Cody, Tena, Jennyfer, Tourdot, Benjamin E., Liu, Benjamin, Holinstat, Michael, Holman, Theodore R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7270142/
https://ncbi.nlm.nih.gov/pubmed/30407793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00889
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