15-Lipoxygenase-1 biosynthesis of 7S,14S-diHDHA implicates 15-lipoxygenase-2 in biosynthesis of resolvin D5

The two oxylipins 7S,14S-dihydroxydocosahexaenoic acid (diHDHA) and 7S,17S-diHDHA [resolvin D5 (RvD5)] have been found in macrophages and infectious inflammatory exudates and are believed to function as specialized pro-resolving mediators (SPMs). Their biosynthesis is thought to proceed through sequ...

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Vydáno v:J Lipid Res
Hlavní autoři: Perry, Steven C., Kalyanaraman, Chakrapani, Tourdot, Benjamin E., Conrad, William S., Akinkugbe, Oluwayomi, Freedman, John Cody, Holinstat, Michael, Jacobson, Matthew P., Holman, Theodore R.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2020
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328043/
https://ncbi.nlm.nih.gov/pubmed/32404334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA120000777
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