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Role of Human 15-Lipoxygenase-2 in the Biosynthesis of the Lipoxin Intermediate, 5S,15S-diHpETE, Implicated with the Altered Positional Specificity of Human 15-Lipoxygenase-1

The oxylipins, 5S,12S-dihydroxy-6E,8Z,10E,14Z-eicosatetraenoic acid (5S,12S-diHETE) and 5S,15S-dihydroxy-6E,8Z,11Z,13E-eicosatetraenoic acid (5S,15S-diHETE), have been identified in cell exudates and have chemotactic activity toward eosinophils and neutrophils. Their biosynthesis has been proposed t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochemistry
Prif Awduron: Perry, Steven C., Horn, Thomas, Tourdot, Benjamin E., Yamaguchi, Adriana, Kalyanaraman, Chakrapani, Conrad, William S., Akinkugbe, Oluwayomi, Holinstat, Michael, Jacobson, Matthew P., Holman, Theodore R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7721368/
https://ncbi.nlm.nih.gov/pubmed/33048542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00622
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