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Structure Activity Relationship Studies of Flavonoids as Potent Inhibitors of Human Platelet 12-hLO, Reticulocyte 15-hLO-1 and Prostate Epithelial 15-hLO-2

Human lipoxygenase (hLO) isozymes have been implicated in a number of disease states and have attracted much attention with respect to their inhibition. One class of inhibitors, the flavonoids, have been shown to be potent lipoxygenase inhibitors but their study has been restricted to those compound...

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Autors principals: Vasquez-Martinez, Yesseny, Ohri, Rachana V., Kenyon, Victor, Holman, Theodore R., Sepúlveda-Boza, Silvia
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2117341/
https://ncbi.nlm.nih.gov/pubmed/17869117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.07.036
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