Molecular Biodynamers: Dynamic Covalent Analogues of Biopolymers

Por Liu, Yun, Lehn, Jean-Marie, Hirsch, Anna K. H.
Publicado no Acc Chem Res (2017)

Structure-Based Optimization of Inhibitors of the Aspartic Protease Endothiapepsin

Por Hartman, Alwin M., Mondal, Milon, Radeva, Nedyalka, Klebe, Gerhard, Hirsch, Anna K. H.
Publicado no Int J Mol Sci (2015)

Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: Fragment‐Based Drug Design Facilitated by Dynamic Combinatorial Chemistry

Por Mondal, Milon, Radeva, Nedyalka, Fanlo‐Virgós, Hugo, Otto, Sijbren, Klebe, Gerhard, Hirsch, Anna K. H.
Publicado no Angew Chem Int Ed Engl (2016)

Saccharide‐Containing Dynamic Proteoids

Por Liu, Yun, Stuart, Marc C. A., Witte, Martin D., Buhler, Eric, Hirsch, Anna K. H.
Publicado no Chemistry (2017)

Terahertz spectroscopy of 2,4,6-trinitrotoluene molecular solids from first principles

Por Azuri, Ido, Hirsch, Anna, Reilly, Anthony M, Tkatchenko, Alexandre, Kendler, Shai, Hod, Oded, Kronik, Leeor
Publicado no Beilstein J Org Chem (2018)

Fragment‐Based Drug Design Facilitated by Protein‐Templated Click Chemistry: Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin

Por Mondal, Milon, Unver, M. Yagiz, Pal, Asish, Bakker, Matthijs, Berrier, Stephan P., Hirsch, Anna K. H.
Publicado no Chemistry (2016)

Dynamic Combinatorial Chemistry to Identify Binders of ThiT, an S‐Component of the Energy‐Coupling Factor Transporter for Thiamine

Por Monjas, Leticia, Swier, Lotteke J. Y. M., Setyawati, Inda, Slotboom, Dirk J., Hirsch, Anna K. H.
Publicado no ChemMedChem (2017)

Phage Display on the Anti‐infective Target 1‐Deoxy‐d‐xylulose‐5‐phosphate Synthase Leads to an Acceptor–Substrate Competitive Peptidic Inhibitor

Por Marcozzi, Alessio, Masini, Tiziana, Zhu, Di, Pesce, Diego, Illarionov, Boris, Fischer, Markus, Herrmann, Andreas, Hirsch, Anna K. H.
Publicado no Chembiochem (2017)

Designed Spiroketal Protein Modulation

Por Scheepstra, Marcel, Andrei, Sebastian A., Unver, M. Yagiz, Hirsch, Anna K. H., Leysen, Seppe, Ottmann, Christian, Brunsveld, Luc, Milroy, Lech‐Gustav
Publicado no Angew Chem Int Ed Engl (2017)

Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease

Por Jay, Taylor R., Hirsch, Anna M., Broihier, Margaret L., Miller, Crystal M., Neilson, Lee E., Ransohoff, Richard M., Lamb, Bruce T., Landreth, Gary E.
Publicado no J Neurosci (2017)

Furoates and Thenoates Inhibit Pyruvate Dehydrogenase Kinase 2 Allosterically by Binding to its Pyruvate Regulatory Site

Por Masini, Tiziana, Birkaya, Barbara, van Dijk, Simon, Mondal, Milon, Hekelaar, Johan, Jäger, Manuel, Terwisscha van Scheltinga, Anke C., Patel, Mulchand S., Hirsch, Anna K. H., Moman, Edelmiro
Publicado no J Enzyme Inhib Med Chem (2016)

Optically functional isoxanthopterin crystals in the mirrored eyes of decapod crustaceans

Por Palmer, Benjamin A., Hirsch, Anna, Brumfeld, Vlad, Aflalo, Eliahu D., Pinkas, Iddo, Sagi, Amir, Rosenne, Shaked, Oron, Dan, Leiserowitz, Leslie, Kronik, Leeor, Weiner, Steve, Addadi, Lia
Publicado no Proc Natl Acad Sci U S A (2018)

Glucansucrase (mutant) enzymes from Lactobacillus reuteri 180 efficiently transglucosylate Stevia component rebaudioside A, resulting in a superior taste

Por te Poele, Evelien M., Devlamynck, Tim, Jäger, Manuel, Gerwig, Gerrit J., Van de Walle, Davy, Dewettinck, Koen, Hirsch, Anna K. H., Kamerling, Johannis P., Soetaert, Wim, Dijkhuizen, Lubbert
Publicado no Sci Rep (2018)

Lipid‐DNAs as Solubilizers of mTHPC

Por Liu, Yun, de Vries, Jan Willem, Liu, Qing, Hartman, Alwin M., Wieland, Gerhard D., Wieczorek, Sebastian, Börner, Hans G., Wiehe, Arno, Buhler, Eric, Stuart, Marc C. A., Browne, Wesley R., Herrmann, Andreas, Hirsch, Anna K. H.
Publicado no Chemistry (2017)