Lipid‐DNAs as Solubilizers of mTHPC

Hydrophobic drug candidates require innovative formulation agents. We designed and synthesized lipid‐DNA polymers containing varying numbers of hydrophobic alkyl chains. The hydrophobicity of these amphiphiles is easily tunable by introducing a defined number of alkyl chain‐modified nucleotides duri...

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Détails bibliographiques
Publié dans:Chemistry
Auteurs principaux: Liu, Yun, de Vries, Jan Willem, Liu, Qing, Hartman, Alwin M., Wieland, Gerhard D., Wieczorek, Sebastian, Börner, Hans G., Wiehe, Arno, Buhler, Eric, Stuart, Marc C. A., Browne, Wesley R., Herrmann, Andreas, Hirsch, Anna K. H.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Communications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814723/
https://ncbi.nlm.nih.gov/pubmed/29194834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201705206
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