Lipid‐DNAs as Solubilizers of mTHPC

Hydrophobic drug candidates require innovative formulation agents. We designed and synthesized lipid‐DNA polymers containing varying numbers of hydrophobic alkyl chains. The hydrophobicity of these amphiphiles is easily tunable by introducing a defined number of alkyl chain‐modified nucleotides duri...

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Dettagli Bibliografici
Pubblicato in:Chemistry
Autori principali: Liu, Yun, de Vries, Jan Willem, Liu, Qing, Hartman, Alwin M., Wieland, Gerhard D., Wieczorek, Sebastian, Börner, Hans G., Wiehe, Arno, Buhler, Eric, Stuart, Marc C. A., Browne, Wesley R., Herrmann, Andreas, Hirsch, Anna K. H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
Soggetti:
Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814723/
https://ncbi.nlm.nih.gov/pubmed/29194834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201705206
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