Photocytotoxicity of mTHPC (Temoporfin) Loaded Polymeric Micelles Mediated by Lipase Catalyzed Degradation

PURPOSE: To study the in vitro photocytotoxicity and cellular uptake of biodegradable polymeric micelles loaded with the photosensitizer mTHPC, including the effect of lipase-catalyzed micelle degradation. METHODS: Micelles of mPEG750-b-oligo(ɛ-caprolactone)(5) (mPEG750-b-OCL(5)) with a hydroxyl (OH...

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Bibliografiske detaljer
Main Authors: Hofman, Jan-Willem, Carstens, Myrra G., van Zeeland, Femke, Helwig, Conny, Flesch, Frits M., Hennink, Wim E., van Nostrum, Cornelus F.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2008
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515570/
https://ncbi.nlm.nih.gov/pubmed/18597164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-008-9590-7
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