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mTHPC-Loaded Extracellular Vesicles Significantly Improve mTHPC Diffusion and Photodynamic Activity in Preclinical Models

Extracellular vesicles (EVs), derived from the cell, display a phospholipid bilayer membrane that protects the cargo molecules from degradation and contributes to increasing their stability in the bloodstream and tumor targeting. EVs are interesting in regard to the delivery of photosensitizers (PSs...

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Vydáno v:Pharmaceutics
Hlavní autoři: Millard, Marie, Posty, Solène, Piffoux, Max, Jasniewski, Jordane, Lassalle, Henri-Pierre, Yakavets, Ilya, Gazeau, Florence, Wilhelm, Claire, Silva, Amanda K. A., Bezdetnaya, Lina
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407764/
https://ncbi.nlm.nih.gov/pubmed/32709026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12070676
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