Dynamic Combinatorial Chemistry to Identify Binders of ThiT, an S‐Component of the Energy‐Coupling Factor Transporter for Thiamine

We applied dynamic combinatorial chemistry (DCC) to identify ligands of ThiT, the S‐component of the energy‐coupling factor (ECF) transporter for thiamine in Lactococcus lactis. We used a pre‐equilibrated dynamic combinatorial library (DCL) and saturation‐transfer difference (STD) NMR spectroscopy t...

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Detaylı Bibliyografya
Yayımlandı:ChemMedChem
Asıl Yazarlar: Monjas, Leticia, Swier, Lotteke J. Y. M., Setyawati, Inda, Slotboom, Dirk J., Hirsch, Anna K. H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Communications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698757/
https://ncbi.nlm.nih.gov/pubmed/28960943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201700440
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