The future of kinase inhibitors for DLBCL?

por Herman, Sarah E. M.
Publicado en Blood (2018)

Pre-clinical modeling of novel therapeutics in chronic lymphocytic leukemia: the tools of the trade

por Herman, Sarah E. M., Wiestner, Adrian
Publicado en Semin Oncol (2016)

Ibrutinib Inhibits VLA-4-Dependent Adhesion in CLL – Reply

por Herman, Sarah E. M., Wiestner, Adrian
Publicado en Clin Cancer Res (2016)

Molecular Pathways: Targeting the Phosphoinositide 3-Kinase (PI3-Kinase) p110 delta in Chronic Lymphocytic Leukemia

por Herman, Sarah E. M., Johnson, Amy J.
Publicado 2012

Treatment with ibrutinib inhibits BTK and VLA-4 dependent adhesion of chronic lymphocytic leukemia cells in vivo

por Herman, Sarah E. M., Mustafa, Rashida Z., Jones, Jade, Wong, Deanna H., Farooqui, Mohammed, Wiestner, Adrian
Publicado en Clin Cancer Res (2015)

Ibrutinib inhibits BCR and NF-κB signaling and reduces tumor proliferation in tissue-resident cells of patients with CLL

por Herman, Sarah E. M., Mustafa, Rashida Z., Gyamfi, Jennifer A., Pittaluga, Stefania, Chang, Stella, Chang, Betty, Farooqui, Mohammed, Wiestner, Adrian
Publicado 2014

Polyreactive Antibodies in CLL Correlate with the Level of Immunoglobulins Not the Number of B Lymphocytes

por Gunti, Sreenivasulu, Herman, Sarah E.M., Gottumukkala, Raju VSRK, Xoing, Ying, Sun, Clare, Carmona, Gilberto, Wiestner, Adrian, Notkins, Abner L.
Publicado en Leuk Lymphoma (2018)

Pharmacodynamic analysis of BTK inhibition in patients with chronic lymphocytic leukemia treated with acalabrutinib

por Alsadhan, Anfal, Cheung, Jean, Gulrajani, Michael, Gaglione, Erika M., Nierman, Pia, Hamdy, Ahmed, Izumi, Raquel, Bibikova, Elena, Patel, Priti, Sun, Clare, Covey, Todd, Herman, Sarah E. M., Wiestner, Adrian
Publicado en Clin Cancer Res (2020)

TLR signaling is activated in lymph-node resident CLL cells and is only partially inhibited by ibrutinib

por Dadashian, Eman L., McAuley, Erin M., Liu, Delong, Shaffer, Arthur L., Young, Ryan M., Iyer, Jessica R., Kruhlak, Michael J., Staudt, Louis M., Wiestner, Adrian, Herman, Sarah E. M.
Publicado en Cancer Res (2018)

The role of phosphatidylinositol 3-kinase-δ in the immunomodulatory effects of lenalidomide in chronic lymphocytic leukemia

por Herman, Sarah E. M., Lapalombella, Rosa, Gordon, Amber L., Ramanunni, Asha, Blum, Kristie A., Jones, Jeffrey, Zhang, Xiaoli, Lannutti, Brian J., Puri, Kamal D., Muthusamy, Natarajan, Byrd, John C., Johnson, Amy J.
Publicado 2011

Ibrutinib antagonizes rituximab-dependent NK cell–mediated cytotoxicity

por Kohrt, Holbrook E., Sagiv-Barfi, Idit, Rafiq, Sarwish, Herman, Sarah E. M., Butchar, Jonathon P., Cheney, Carolyn, Zhang, Xiaoli, Buggy, Joseph J., Muthusamy, Natarajan, Levy, Ronald, Johnson, Amy J., Byrd, John C.
Publicado 2014

Combined BTK and PI3Kδ inhibition with acalabrutinib and ACP-319 improves survival and tumor control in CLL mouse model

por Niemann, Carsten U., Mora-Jensen, Helena I., Dadashian, Eman L., Krantz, Fanny, Covey, Todd, Chen, Shih-Shih, Chiorazzi, Nicholas, Izumi, Raquel, Ulrich, Roger, Lannutti, Brian J., Wiestner, Adrian, Herman, Sarah E. M.
Publicado en Clin Cancer Res (2017)

Prediction of Outcome in Patients With Chronic Lymphocytic Leukemia Treated With Ibrutinib: Development and Validation of a Four-Factor Prognostic Model

por Ahn, Inhye E., Tian, Xin, Ipe, David, Cheng, Mei, Albitar, Maher, Tsao, L. Claire, Zhang, Lei, Ma, Wanlong, Herman, Sarah E. M., Gaglione, Erika M., Soto, Susan, Dean, James P., Wiestner, Adrian
Publicado en J Clin Oncol (2021)

Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765

por Herman, Sarah E. M., Gordon, Amber L., Hertlein, Erin, Ramanunni, Asha, Zhang, Xiaoli, Jaglowski, Samantha, Flynn, Joseph, Jones, Jeffrey, Blum, Kristie A., Buggy, Joseph J., Hamdy, Ahmed, Johnson, Amy J., Byrd, John C.
Publicado 2011

A CD19/CD3 bispecific antibody for effective immunotherapy of chronic lymphocytic leukemia in the ibrutinib era

por Robinson, Hannah R., Qi, Junpeng, Cook, Erika M., Nichols, Cydney, Dadashian, Eman L., Underbayev, Chingiz, Herman, Sarah E. M., Saba, Nakhle S., Keyvanfar, Keyvan, Sun, Clare, Ahn, Inhye E., Baskar, Sivasubramanian, Rader, Christoph, Wiestner, Adrian
Publicado en Blood (2018)

Pharmacokinetics and Tissue Disposition of Lenalidomide in Mice

por Rozewski, Darlene M., Herman, Sarah E. M., Towns, William H., Mahoney, Emilia, Stefanovski, Matthew R., Shin, Jungook D., Yang, Xiaoxia, Gao, Yue, Li, Xiaobai, Jarjoura, David, Byrd, John C., Johnson, Amy J., Phelps, Mitch A.
Publicado 2012

MALT1 inhibition is efficacious in both naïve and ibrutinib-resistant chronic lymphocytic leukemia

por Saba, Nakhle S., Wong, Deanna H., Tanios, Georges, Iyer, Jessica R., Lobelle-Rich, Patricia, Dadashian, Eman L., Liu, Delong, Fontan, Lorena, Flemington, Erik K., Nichols, Cydney M., Underbayev, Chingiz, Safah, Hana, Melnick, Ari, Wiestner, Adrian, Herman, Sarah E. M.
Publicado en Cancer Res (2017)

Targeted nanoparticle delivery overcomes off-target immunostimulatory effects of oligonucleotides and improves therapeutic efficacy in chronic lymphocytic leukemia

por Yu, Bo, Mao, Yicheng, Bai, Li-Yuan, Herman, Sarah E. M., Wang, Xinmei, Ramanunni, Asha, Jin, Yan, Mo, Xiaokui, Cheney, Carolyn, Chan, Kenneth K., Jarjoura, David, Marcucci, Guido, Lee, Robert J., Byrd, John C., Lee, L. James, Muthusamy, Natarajan
Publicado 2013

Egress of CD19(+)CD5(+) cells into peripheral blood following treatment with the Bruton tyrosine kinase inhibitor ibrutinib in mantle cell lymphoma patients

por Chang, Betty Y., Francesco, Michelle, De Rooij, Martin F. M., Magadala, Padmaja, Steggerda, Susanne M., Huang, Min Mei, Kuil, Annemieke, Herman, Sarah E. M., Chang, Stella, Pals, Steven T., Wilson, Wyndham, Wiestner, Adrian, Spaargaren, Marcel, Buggy, Joseph J., Elias, Laurence
Publicado 2013

Modeling Tumor-Host Interactions of Chronic Lymphocytic Leukemia in Xenografted Mice to Study Tumor Biology and Evaluate Targeted Therapy

por Herman, Sarah E. M., Sun, Xiameng, McAuley, Erin M., Hsieh, Matthew M., Pittaluga, Stefania, Raffeld, Mark, Liu, Delong, Keyvanfar, Keyvan, Chapman, Colby M., Chen, Jichun, Buggy, Joseph J., Aue, Georg, Tisdale, John F., Pérez-Galán, Patricia, Wiestner, Adrian
Publicado 2013