লোডিং...
Targeted nanoparticle delivery overcomes off-target immunostimulatory effects of oligonucleotides and improves therapeutic efficacy in chronic lymphocytic leukemia
Several RNA-targeted therapeutics, including antisense oligonucleotides (ONs), small interfering RNAs, and miRNAs, constitute immunostimulatory CpG motifs as an integral part of their design. The limited success with free antisense ONs in hematologic malignancies in recent clinical trials has been a...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , , , , , , , , , , , , , |
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| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
American Society of Hematology
2013
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3538326/ https://ncbi.nlm.nih.gov/pubmed/23165478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-407742 |
| ট্যাগগুলো: |
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