Targeted drug delivery and cross-linking induced apoptosis with anti-CD37 based dual-ligand immunoliposomes in B chronic lymphocytic leukemia cells

Despite advances in chemo- and immunotherapeutic agents for B chronic lymphocytic leukemia (B-CLL), the undesirable adverse side effects due to non-specific cellular uptake remain to be addressed. We identified anti-CD37 monoclonal antibody immunoliposomes (ILs) as vehicles for targeted delivery to...

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Main Authors: Yu, Bo, Mao, Yicheng, Yuan, Yuan, Yue, Chaofang, Wang, Xinmei, Mo, Xiaokui, Jarjoura, David, Paulaitis, Michael, Lee, Robert J., Byrd, John C., Lee, L. James, Muthusamy, Natarajan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756150/
https://ncbi.nlm.nih.gov/pubmed/23726226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.04.063
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