The role of phosphatidylinositol 3-kinase-δ in the immunomodulatory effects of lenalidomide in chronic lymphocytic leukemia

In patients with chronic lymphocytic leukemia (CLL), lenalidomide can promote humoral immune responses but also induces a distinct disease-specific toxicity of tumor flare and cytokine release. These CLL-specific events result from increased expression of costimulatory molecules on B cells. Here we...

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書誌詳細
主要な著者: Herman, Sarah E. M., Lapalombella, Rosa, Gordon, Amber L., Ramanunni, Asha, Blum, Kristie A., Jones, Jeffrey, Zhang, Xiaoli, Lannutti, Brian J., Puri, Kamal D., Muthusamy, Natarajan, Byrd, John C., Johnson, Amy J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2011
主題:
Lymphoid Neoplasia
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087482/
https://ncbi.nlm.nih.gov/pubmed/21378270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-315705
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