The role of phosphatidylinositol 3-kinase-δ in the immunomodulatory effects of lenalidomide in chronic lymphocytic leukemia

In patients with chronic lymphocytic leukemia (CLL), lenalidomide can promote humoral immune responses but also induces a distinct disease-specific toxicity of tumor flare and cytokine release. These CLL-specific events result from increased expression of costimulatory molecules on B cells. Here we...

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Detalhes bibliográficos
Main Authors: Herman, Sarah E. M., Lapalombella, Rosa, Gordon, Amber L., Ramanunni, Asha, Blum, Kristie A., Jones, Jeffrey, Zhang, Xiaoli, Lannutti, Brian J., Puri, Kamal D., Muthusamy, Natarajan, Byrd, John C., Johnson, Amy J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087482/
https://ncbi.nlm.nih.gov/pubmed/21378270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-315705
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