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Molecular Pathways: Targeting the Phosphoinositide 3-Kinase (PI3-Kinase) p110 delta in Chronic Lymphocytic Leukemia

The advent of targeted therapy, specifically to the B-cell receptor (BCR), has changed the convention for the treatment of chronic lymphocytic leukemia (CLL). The PI3K pathway, activated upstream by the BCR, receptor tyrosine kinases and cytokine receptors, has been a potential target for a multitud...

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Detalhes bibliográficos
Main Authors: Herman, Sarah E. M., Johnson, Amy J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425377/
https://ncbi.nlm.nih.gov/pubmed/22711705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1402
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