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Molecular Pathways: Targeting the Phosphoinositide 3-Kinase (PI3-Kinase) p110 delta in Chronic Lymphocytic Leukemia

The advent of targeted therapy, specifically to the B-cell receptor (BCR), has changed the convention for the treatment of chronic lymphocytic leukemia (CLL). The PI3K pathway, activated upstream by the BCR, receptor tyrosine kinases and cytokine receptors, has been a potential target for a multitud...

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書誌詳細
主要な著者: Herman, Sarah E. M., Johnson, Amy J.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425377/
https://ncbi.nlm.nih.gov/pubmed/22711705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1402
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