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Targeting the phosphoinositide 3-kinase (PI3K) pathway in cancer

The phosphoinositide 3-kinase (PI3K) pathway, a critical signal transduction system linking oncogenes and multiple receptor classes to many essential cellular functions, is perhaps the most commonly activated signaling pathway in human cancer. This pathway thus presents both an opportunity and a cha...

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Bibliografische gegevens
Hoofdauteurs: Liu, Pixu, Cheng, Hailing, Roberts, Thomas M., Zhao, Jean J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142564/
https://ncbi.nlm.nih.gov/pubmed/19644473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd2926
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