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Targeting the phosphoinositide 3-kinase (PI3K) pathway in cancer

The phosphoinositide 3-kinase (PI3K) pathway, a critical signal transduction system linking oncogenes and multiple receptor classes to many essential cellular functions, is perhaps the most commonly activated signaling pathway in human cancer. This pathway thus presents both an opportunity and a cha...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Liu, Pixu, Cheng, Hailing, Roberts, Thomas M., Zhao, Jean J.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142564/
https://ncbi.nlm.nih.gov/pubmed/19644473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd2926
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