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Targeting the PI3K signaling pathway in cancer

The PI3K pathway is activated in a variety of different human cancers, and inhibitors of this pathway are under active development as anti-cancer therapeutics. In this review, we discuss the data supporting the use of PI3K pathway inhibitors in genetically and clinically defined cancers. This review...

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Bibliografische gegevens
Hoofdauteurs: Wong, Kwok-Kin, Engelman, Jeffrey A, Cantley, Lewis C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822054/
https://ncbi.nlm.nih.gov/pubmed/20006486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2009.11.002
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