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Targeting the PI3K pathway for cancer therapy

The PI3K pathway plays an important role in key cellular functions such as cell growth, proliferation and survival. Genetic and epigenetic alterations in different pathway components lead to aberrant pathway activation and have been observed in high frequencies in various tumor types. Consequently,...

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Vydáno v:Future Med Chem
Hlavní autoři: Sadeghi, Navid, Gerber, David E
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276042/
https://ncbi.nlm.nih.gov/pubmed/22709255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.12.56
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