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Targeting the PI3K pathway for cancer therapy

The PI3K pathway plays an important role in key cellular functions such as cell growth, proliferation and survival. Genetic and epigenetic alterations in different pathway components lead to aberrant pathway activation and have been observed in high frequencies in various tumor types. Consequently,...

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Detalhes bibliográficos
Publicado no:Future Med Chem
Main Authors: Sadeghi, Navid, Gerber, David E
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276042/
https://ncbi.nlm.nih.gov/pubmed/22709255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.12.56
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