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Molecular Pathways: Targeting the PI3K Pathway in Cancer—BET Inhibitors to the Rescue

The phosphoinositide 3-kinase (PI3K) signaling pathway is a complex and tightly regulated network that is critical for many physiological processes such as cell growth, proliferation, metabolism and survival. Aberrant activation of this pathway can occur through mutation of almost any of its major n...

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Библиографические подробности
Опубликовано в: :Clin Cancer Res
Главные авторы: Stratikopoulos, Elias E., Parsons, Ramon E.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896088/
https://ncbi.nlm.nih.gov/pubmed/27250929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2389
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