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Molecular Pathways: Targeting the PI3K Pathway in Cancer—BET Inhibitors to the Rescue

The phosphoinositide 3-kinase (PI3K) signaling pathway is a complex and tightly regulated network that is critical for many physiological processes such as cell growth, proliferation, metabolism and survival. Aberrant activation of this pathway can occur through mutation of almost any of its major n...

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Dades bibliogràfiques
Publicat a:Clin Cancer Res
Autors principals: Stratikopoulos, Elias E., Parsons, Ramon E.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896088/
https://ncbi.nlm.nih.gov/pubmed/27250929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2389
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