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Molecular Pathways: Targeting the PI3K Pathway in Cancer—BET Inhibitors to the Rescue

The phosphoinositide 3-kinase (PI3K) signaling pathway is a complex and tightly regulated network that is critical for many physiological processes such as cell growth, proliferation, metabolism and survival. Aberrant activation of this pathway can occur through mutation of almost any of its major n...

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Bibliographic Details
Published in:Clin Cancer Res
Main Authors: Stratikopoulos, Elias E., Parsons, Ramon E.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896088/
https://ncbi.nlm.nih.gov/pubmed/27250929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2389
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