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Molecular Pathways: Targeting the PI3K Pathway in Cancer—BET Inhibitors to the Rescue

The phosphoinositide 3-kinase (PI3K) signaling pathway is a complex and tightly regulated network that is critical for many physiological processes such as cell growth, proliferation, metabolism and survival. Aberrant activation of this pathway can occur through mutation of almost any of its major n...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Stratikopoulos, Elias E., Parsons, Ramon E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896088/
https://ncbi.nlm.nih.gov/pubmed/27250929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2389
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