The future of kinase inhibitors for DLBCL?

بواسطة Herman, Sarah E. M.
الحاوية / القاعدة Blood (2018)

Pre-clinical modeling of novel therapeutics in chronic lymphocytic leukemia: the tools of the trade

بواسطة Herman, Sarah E. M., Wiestner, Adrian
الحاوية / القاعدة Semin Oncol (2016)

Ibrutinib Inhibits VLA-4-Dependent Adhesion in CLL – Reply

بواسطة Herman, Sarah E. M., Wiestner, Adrian
الحاوية / القاعدة Clin Cancer Res (2016)

Molecular Pathways: Targeting the Phosphoinositide 3-Kinase (PI3-Kinase) p110 delta in Chronic Lymphocytic Leukemia

بواسطة Herman, Sarah E. M., Johnson, Amy J.
منشور في 2012

Treatment with ibrutinib inhibits BTK and VLA-4 dependent adhesion of chronic lymphocytic leukemia cells in vivo

بواسطة Herman, Sarah E. M., Mustafa, Rashida Z., Jones, Jade, Wong, Deanna H., Farooqui, Mohammed, Wiestner, Adrian
الحاوية / القاعدة Clin Cancer Res (2015)

Ibrutinib inhibits BCR and NF-κB signaling and reduces tumor proliferation in tissue-resident cells of patients with CLL

بواسطة Herman, Sarah E. M., Mustafa, Rashida Z., Gyamfi, Jennifer A., Pittaluga, Stefania, Chang, Stella, Chang, Betty, Farooqui, Mohammed, Wiestner, Adrian
منشور في 2014

Polyreactive Antibodies in CLL Correlate with the Level of Immunoglobulins Not the Number of B Lymphocytes

بواسطة Gunti, Sreenivasulu, Herman, Sarah E.M., Gottumukkala, Raju VSRK, Xoing, Ying, Sun, Clare, Carmona, Gilberto, Wiestner, Adrian, Notkins, Abner L.
الحاوية / القاعدة Leuk Lymphoma (2018)

Pharmacodynamic analysis of BTK inhibition in patients with chronic lymphocytic leukemia treated with acalabrutinib

بواسطة Alsadhan, Anfal, Cheung, Jean, Gulrajani, Michael, Gaglione, Erika M., Nierman, Pia, Hamdy, Ahmed, Izumi, Raquel, Bibikova, Elena, Patel, Priti, Sun, Clare, Covey, Todd, Herman, Sarah E. M., Wiestner, Adrian
الحاوية / القاعدة Clin Cancer Res (2020)

TLR signaling is activated in lymph-node resident CLL cells and is only partially inhibited by ibrutinib

بواسطة Dadashian, Eman L., McAuley, Erin M., Liu, Delong, Shaffer, Arthur L., Young, Ryan M., Iyer, Jessica R., Kruhlak, Michael J., Staudt, Louis M., Wiestner, Adrian, Herman, Sarah E. M.
الحاوية / القاعدة Cancer Res (2018)

The role of phosphatidylinositol 3-kinase-δ in the immunomodulatory effects of lenalidomide in chronic lymphocytic leukemia

بواسطة Herman, Sarah E. M., Lapalombella, Rosa, Gordon, Amber L., Ramanunni, Asha, Blum, Kristie A., Jones, Jeffrey, Zhang, Xiaoli, Lannutti, Brian J., Puri, Kamal D., Muthusamy, Natarajan, Byrd, John C., Johnson, Amy J.
منشور في 2011

Ibrutinib antagonizes rituximab-dependent NK cell–mediated cytotoxicity

بواسطة Kohrt, Holbrook E., Sagiv-Barfi, Idit, Rafiq, Sarwish, Herman, Sarah E. M., Butchar, Jonathon P., Cheney, Carolyn, Zhang, Xiaoli, Buggy, Joseph J., Muthusamy, Natarajan, Levy, Ronald, Johnson, Amy J., Byrd, John C.
منشور في 2014

Combined BTK and PI3Kδ inhibition with acalabrutinib and ACP-319 improves survival and tumor control in CLL mouse model

بواسطة Niemann, Carsten U., Mora-Jensen, Helena I., Dadashian, Eman L., Krantz, Fanny, Covey, Todd, Chen, Shih-Shih, Chiorazzi, Nicholas, Izumi, Raquel, Ulrich, Roger, Lannutti, Brian J., Wiestner, Adrian, Herman, Sarah E. M.
الحاوية / القاعدة Clin Cancer Res (2017)

Prediction of Outcome in Patients With Chronic Lymphocytic Leukemia Treated With Ibrutinib: Development and Validation of a Four-Factor Prognostic Model

بواسطة Ahn, Inhye E., Tian, Xin, Ipe, David, Cheng, Mei, Albitar, Maher, Tsao, L. Claire, Zhang, Lei, Ma, Wanlong, Herman, Sarah E. M., Gaglione, Erika M., Soto, Susan, Dean, James P., Wiestner, Adrian
الحاوية / القاعدة J Clin Oncol (2021)

Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765

بواسطة Herman, Sarah E. M., Gordon, Amber L., Hertlein, Erin, Ramanunni, Asha, Zhang, Xiaoli, Jaglowski, Samantha, Flynn, Joseph, Jones, Jeffrey, Blum, Kristie A., Buggy, Joseph J., Hamdy, Ahmed, Johnson, Amy J., Byrd, John C.
منشور في 2011

A CD19/CD3 bispecific antibody for effective immunotherapy of chronic lymphocytic leukemia in the ibrutinib era

بواسطة Robinson, Hannah R., Qi, Junpeng, Cook, Erika M., Nichols, Cydney, Dadashian, Eman L., Underbayev, Chingiz, Herman, Sarah E. M., Saba, Nakhle S., Keyvanfar, Keyvan, Sun, Clare, Ahn, Inhye E., Baskar, Sivasubramanian, Rader, Christoph, Wiestner, Adrian
الحاوية / القاعدة Blood (2018)

Pharmacokinetics and Tissue Disposition of Lenalidomide in Mice

بواسطة Rozewski, Darlene M., Herman, Sarah E. M., Towns, William H., Mahoney, Emilia, Stefanovski, Matthew R., Shin, Jungook D., Yang, Xiaoxia, Gao, Yue, Li, Xiaobai, Jarjoura, David, Byrd, John C., Johnson, Amy J., Phelps, Mitch A.
منشور في 2012

MALT1 inhibition is efficacious in both naïve and ibrutinib-resistant chronic lymphocytic leukemia

بواسطة Saba, Nakhle S., Wong, Deanna H., Tanios, Georges, Iyer, Jessica R., Lobelle-Rich, Patricia, Dadashian, Eman L., Liu, Delong, Fontan, Lorena, Flemington, Erik K., Nichols, Cydney M., Underbayev, Chingiz, Safah, Hana, Melnick, Ari, Wiestner, Adrian, Herman, Sarah E. M.
الحاوية / القاعدة Cancer Res (2017)

Targeted nanoparticle delivery overcomes off-target immunostimulatory effects of oligonucleotides and improves therapeutic efficacy in chronic lymphocytic leukemia

بواسطة Yu, Bo, Mao, Yicheng, Bai, Li-Yuan, Herman, Sarah E. M., Wang, Xinmei, Ramanunni, Asha, Jin, Yan, Mo, Xiaokui, Cheney, Carolyn, Chan, Kenneth K., Jarjoura, David, Marcucci, Guido, Lee, Robert J., Byrd, John C., Lee, L. James, Muthusamy, Natarajan
منشور في 2013

Egress of CD19(+)CD5(+) cells into peripheral blood following treatment with the Bruton tyrosine kinase inhibitor ibrutinib in mantle cell lymphoma patients

بواسطة Chang, Betty Y., Francesco, Michelle, De Rooij, Martin F. M., Magadala, Padmaja, Steggerda, Susanne M., Huang, Min Mei, Kuil, Annemieke, Herman, Sarah E. M., Chang, Stella, Pals, Steven T., Wilson, Wyndham, Wiestner, Adrian, Spaargaren, Marcel, Buggy, Joseph J., Elias, Laurence
منشور في 2013

Modeling Tumor-Host Interactions of Chronic Lymphocytic Leukemia in Xenografted Mice to Study Tumor Biology and Evaluate Targeted Therapy

بواسطة Herman, Sarah E. M., Sun, Xiameng, McAuley, Erin M., Hsieh, Matthew M., Pittaluga, Stefania, Raffeld, Mark, Liu, Delong, Keyvanfar, Keyvan, Chapman, Colby M., Chen, Jichun, Buggy, Joseph J., Aue, Georg, Tisdale, John F., Pérez-Galán, Patricia, Wiestner, Adrian
منشور في 2013