Replication Protein A Prohibits Diffusion of the PCNA Sliding Clamp along Single-Stranded DNA

door Hedglin, Mark, Benkovic, Stephen J.
Gepubliceerd in Biochemistry (2017)

Regulation of Rad6/Rad18 Activity During DNA Damage Tolerance

door Hedglin, Mark, Benkovic, Stephen J.
Gepubliceerd in Annu Rev Biophys (2015)

Eukaryotic Translesion DNA Synthesis on the Leading and Lagging Strands: Unique Detours Around the Same Obstacle

door Hedglin, Mark, Benkovic, Stephen J.
Gepubliceerd in Chem Rev (2017)

Human Alkyladenine DNA Glycosylase Employs a Processive Search for DNA Damage

door Hedglin, Mark, O’Brien, Patrick J.
Gepubliceerd in 2008

Hopping Enables a DNA Repair Glycosylase to Search Both Strands and Bypass a Bound Protein

door Hedglin, Mark, O'Brien, Patrick J.
Gepubliceerd in 2010

Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase

door Shin, Yeonoh, Hedglin, Mark, Murakami, Katsuhiko S
Gepubliceerd in Nucleic Acids Res (2020)

Replication Clamps and Clamp Loaders

door Hedglin, Mark, Kumar, Ravindra, Benkovic, Stephen J.
Gepubliceerd in 2013

Stability of the human polymerase δ holoenzyme and its implications in lagging strand DNA synthesis

door Hedglin, Mark, Pandey, Binod, Benkovic, Stephen J.
Gepubliceerd in Proc Natl Acad Sci U S A (2016)

Characterization of human translesion DNA synthesis across a UV-induced DNA lesion

door Hedglin, Mark, Pandey, Binod, Benkovic, Stephen J
Gepubliceerd in eLife (2016)

Monitoring the Retention of Human PCNA at Primer/Template junctions by Proteins that Bind Single-stranded DNA

door Hedglin, Mark, Aitha, Mahesh, Benkovic, Stephen J.
Gepubliceerd in Biochemistry (2017)

Isolating Contributions from Intersegmental Transfer to DNA Searching by Alkyladenine DNA Glycosylase

door Hedglin, Mark, Zhang, Yaru, O'Brien, Patrick J.
Gepubliceerd in 2013

Probing the DNA Structural Requirements for Facilitated Diffusion

door Hedglin, Mark, Zhang, Yaru, O’Brien, Patrick J.
Gepubliceerd in Biochemistry (2014)

Stepwise assembly of the human replicative polymerase holoenzyme

door Hedglin, Mark, Perumal, Senthil K, Hu, Zhenxin, Benkovic, Stephen
Gepubliceerd in 2013

Replication protein A dynamically regulates monoubiquitination of proliferating cell nuclear antigen

door Hedglin, Mark, Aitha, Mahesh, Pedley, Anthony, Benkovic, Stephen J.
Gepubliceerd in J Biol Chem (2019)

PCNA Monoubiquitination Is Regulated by Diffusion of Rad6/Rad18 Complexes along RPA Filaments

door Li, Mingjie, Sengupta, Bhaswati, Benkovic, Stephen J., Lee, Tae Hee, Hedglin, Mark
Gepubliceerd in Biochemistry (2020)

Structure of the human clamp loader reveals an autoinhibited conformation of a substrate-bound AAA+ switch

door Gaubitz, Christl, Liu, Xingchen, Magrino, Joseph, Stone, Nicholas P., Landeck, Jacob, Hedglin, Mark, Kelch, Brian A.
Gepubliceerd in Proc Natl Acad Sci U S A (2020)