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Regulation of Rad6/Rad18 Activity During DNA Damage Tolerance

Replicative polymerases (pols) cannot accommodate damaged template bases, and these pols stall when such offenses are encountered during S phase. Rather than repairing the damaged base, replication past it may proceed via one of two DNA damage tolerance (DDT) pathways, allowing replicative DNA synth...

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Bibliografische gegevens
Gepubliceerd in:Annu Rev Biophys
Hoofdauteurs: Hedglin, Mark, Benkovic, Stephen J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592839/
https://ncbi.nlm.nih.gov/pubmed/26098514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biophys-060414-033841
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