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Regulation of Rad6/Rad18 Activity During DNA Damage Tolerance
Replicative polymerases (pols) cannot accommodate damaged template bases, and these pols stall when such offenses are encountered during S phase. Rather than repairing the damaged base, replication past it may proceed via one of two DNA damage tolerance (DDT) pathways, allowing replicative DNA synth...
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Publicado no: | Annu Rev Biophys |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5592839/ https://ncbi.nlm.nih.gov/pubmed/26098514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biophys-060414-033841 |
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