Replication Protein A Prohibits Diffusion of the PCNA Sliding Clamp along Single-Stranded DNA

por Hedglin, Mark, Benkovic, Stephen J.
Publicado en Biochemistry (2017)

Regulation of Rad6/Rad18 Activity During DNA Damage Tolerance

por Hedglin, Mark, Benkovic, Stephen J.
Publicado en Annu Rev Biophys (2015)

Eukaryotic Translesion DNA Synthesis on the Leading and Lagging Strands: Unique Detours Around the Same Obstacle

por Hedglin, Mark, Benkovic, Stephen J.
Publicado en Chem Rev (2017)

Human Alkyladenine DNA Glycosylase Employs a Processive Search for DNA Damage

por Hedglin, Mark, O’Brien, Patrick J.
Publicado 2008

Hopping Enables a DNA Repair Glycosylase to Search Both Strands and Bypass a Bound Protein

por Hedglin, Mark, O'Brien, Patrick J.
Publicado 2010

Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase

por Shin, Yeonoh, Hedglin, Mark, Murakami, Katsuhiko S
Publicado en Nucleic Acids Res (2020)

Replication Clamps and Clamp Loaders

por Hedglin, Mark, Kumar, Ravindra, Benkovic, Stephen J.
Publicado 2013

Stability of the human polymerase δ holoenzyme and its implications in lagging strand DNA synthesis

por Hedglin, Mark, Pandey, Binod, Benkovic, Stephen J.
Publicado en Proc Natl Acad Sci U S A (2016)

Characterization of human translesion DNA synthesis across a UV-induced DNA lesion

por Hedglin, Mark, Pandey, Binod, Benkovic, Stephen J
Publicado en eLife (2016)

Monitoring the Retention of Human PCNA at Primer/Template junctions by Proteins that Bind Single-stranded DNA

por Hedglin, Mark, Aitha, Mahesh, Benkovic, Stephen J.
Publicado en Biochemistry (2017)

Isolating Contributions from Intersegmental Transfer to DNA Searching by Alkyladenine DNA Glycosylase

por Hedglin, Mark, Zhang, Yaru, O'Brien, Patrick J.
Publicado 2013

Probing the DNA Structural Requirements for Facilitated Diffusion

por Hedglin, Mark, Zhang, Yaru, O’Brien, Patrick J.
Publicado en Biochemistry (2014)

Stepwise assembly of the human replicative polymerase holoenzyme

por Hedglin, Mark, Perumal, Senthil K, Hu, Zhenxin, Benkovic, Stephen
Publicado 2013

Replication protein A dynamically regulates monoubiquitination of proliferating cell nuclear antigen

por Hedglin, Mark, Aitha, Mahesh, Pedley, Anthony, Benkovic, Stephen J.
Publicado en J Biol Chem (2019)

PCNA Monoubiquitination Is Regulated by Diffusion of Rad6/Rad18 Complexes along RPA Filaments

por Li, Mingjie, Sengupta, Bhaswati, Benkovic, Stephen J., Lee, Tae Hee, Hedglin, Mark
Publicado en Biochemistry (2020)

Structure of the human clamp loader reveals an autoinhibited conformation of a substrate-bound AAA+ switch

por Gaubitz, Christl, Liu, Xingchen, Magrino, Joseph, Stone, Nicholas P., Landeck, Jacob, Hedglin, Mark, Kelch, Brian A.
Publicado en Proc Natl Acad Sci U S A (2020)