Replication Protein A Prohibits Diffusion of the PCNA Sliding Clamp along Single-Stranded DNA

von Hedglin, Mark, Benkovic, Stephen J.
Veröffentlicht in Biochemistry (2017)

Regulation of Rad6/Rad18 Activity During DNA Damage Tolerance

von Hedglin, Mark, Benkovic, Stephen J.
Veröffentlicht in Annu Rev Biophys (2015)

Eukaryotic Translesion DNA Synthesis on the Leading and Lagging Strands: Unique Detours Around the Same Obstacle

von Hedglin, Mark, Benkovic, Stephen J.
Veröffentlicht in Chem Rev (2017)

Human Alkyladenine DNA Glycosylase Employs a Processive Search for DNA Damage

von Hedglin, Mark, O’Brien, Patrick J.
Veröffentlicht 2008

Hopping Enables a DNA Repair Glycosylase to Search Both Strands and Bypass a Bound Protein

von Hedglin, Mark, O'Brien, Patrick J.
Veröffentlicht 2010

Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase

von Shin, Yeonoh, Hedglin, Mark, Murakami, Katsuhiko S
Veröffentlicht in Nucleic Acids Res (2020)

Replication Clamps and Clamp Loaders

von Hedglin, Mark, Kumar, Ravindra, Benkovic, Stephen J.
Veröffentlicht 2013

Stability of the human polymerase δ holoenzyme and its implications in lagging strand DNA synthesis

von Hedglin, Mark, Pandey, Binod, Benkovic, Stephen J.
Veröffentlicht in Proc Natl Acad Sci U S A (2016)

Characterization of human translesion DNA synthesis across a UV-induced DNA lesion

von Hedglin, Mark, Pandey, Binod, Benkovic, Stephen J
Veröffentlicht in eLife (2016)

Monitoring the Retention of Human PCNA at Primer/Template junctions by Proteins that Bind Single-stranded DNA

von Hedglin, Mark, Aitha, Mahesh, Benkovic, Stephen J.
Veröffentlicht in Biochemistry (2017)

Isolating Contributions from Intersegmental Transfer to DNA Searching by Alkyladenine DNA Glycosylase

von Hedglin, Mark, Zhang, Yaru, O'Brien, Patrick J.
Veröffentlicht 2013

Probing the DNA Structural Requirements for Facilitated Diffusion

von Hedglin, Mark, Zhang, Yaru, O’Brien, Patrick J.
Veröffentlicht in Biochemistry (2014)

Stepwise assembly of the human replicative polymerase holoenzyme

von Hedglin, Mark, Perumal, Senthil K, Hu, Zhenxin, Benkovic, Stephen
Veröffentlicht 2013

Replication protein A dynamically regulates monoubiquitination of proliferating cell nuclear antigen

von Hedglin, Mark, Aitha, Mahesh, Pedley, Anthony, Benkovic, Stephen J.
Veröffentlicht in J Biol Chem (2019)

PCNA Monoubiquitination Is Regulated by Diffusion of Rad6/Rad18 Complexes along RPA Filaments

von Li, Mingjie, Sengupta, Bhaswati, Benkovic, Stephen J., Lee, Tae Hee, Hedglin, Mark
Veröffentlicht in Biochemistry (2020)

Structure of the human clamp loader reveals an autoinhibited conformation of a substrate-bound AAA+ switch

von Gaubitz, Christl, Liu, Xingchen, Magrino, Joseph, Stone, Nicholas P., Landeck, Jacob, Hedglin, Mark, Kelch, Brian A.
Veröffentlicht in Proc Natl Acad Sci U S A (2020)