Positioning Metabolism as a Central Player in the Diabetic Heart

由 Mereweather, Laura J., Montes Aparicio, Claudia N., Heather, Lisa C.
發表在 J Lipid Atheroscler (2020)

In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance

由 Schroeder, Marie A., Cochlin, Lowri E., Heather, Lisa C., Clarke, Kieran, Radda, George K., Tyler, Damian J.
出版 2008

Changes in Cardiac Substrate Transporters and Metabolic Proteins Mirror the Metabolic Shift in Patients with Aortic Stenosis

由 Heather, Lisa C., Howell, Neil J., Emmanuel, Yaso, Cole, Mark A., Frenneaux, Michael P., Pagano, Domenico, Clarke, Kieran
出版 2011

Determining In Vivo Regulation of Cardiac Pyruvate Dehydrogenase Based on Label Flux from Hyperpolarized [1-(13)C]Pyruvate

由 Schroeder, Marie A., Atherton, Helen J., Heather, Lisa C., Griffin, Julian L., Clarke, Kieran, Radda, George K., Tyler, Damian J.
發表在 NMR Biomed (2011)

Simultaneous in vivo assessment of cardiac and hepatic metabolism in the diabetic rat using hyperpolarized MRS

由 Le Page, Lydia M., Ball, Daniel R., Ball, Vicky, Dodd, Michael S., Miller, Jack J., Heather, Lisa C., Tyler, Damian J.
發表在 NMR Biomed (2016)

Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin

由 Mansor, Latt S, Gonzalez, Eileen R, Cole, Mark A, Tyler, Damian J, Beeson, Jessica H, Clarke, Kieran, Carr, Carolyn A, Heather, Lisa C
出版 2013

The Role of PDH Inhibition in the Development of Hypertrophy in the Hyperthyroid Rat Heart: A Combined MRI and Hyperpolarized MRS Study

由 Atherton, Helen J., Dodd, Michael S., Heather, Lisa C., Schroeder, Marie A., Griffin, Julian L., Radda, George K., Clarke, Kieran, Tyler, Damian J.
發表在 Circulation (2011)

The von Hippel-Lindau Chuvash mutation in mice alters cardiac substrate and high-energy phosphate metabolism

由 Slingo, Mary, Cole, Mark, Carr, Carolyn, Curtis, Mary K., Dodd, Michael, Giles, Lucia, Heather, Lisa C., Tyler, Damian, Clarke, Kieran, Robbins, Peter A.
發表在 Am J Physiol Heart Circ Physiol (2016)

Rescue of myocardial energetic dysfunction in diabetes through the correction of mitochondrial hyperacetylation by honokiol

由 Kerr, Matthew, Miller, Jack J., Thapa, Dharendra, Stiewe, Sophie, Timm, Kerstin N., Aparicio, Claudia N. Montes, Scott, Iain, Tyler, Damian J., Heather, Lisa C.
發表在 JCI Insight (2020)

Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined (13)C Hyperpolarized Magnetic Resonance and Echocardiography Study

由 Le Page, Lydia M., Rider, Oliver J., Lewis, Andrew J., Ball, Vicky, Clarke, Kieran, Johansson, Edvin, Carr, Carolyn A., Heather, Lisa C., Tyler, Damian J.
發表在 Diabetes (2015)

Real-time assessment of Krebs cycle metabolism using hyperpolarized (13)C magnetic resonance spectroscopy

由 Schroeder, Marie A., Atherton, Helen J., Ball, Daniel R., Cole, Mark A., Heather, Lisa C., Griffin, Julian L., Clarke, Kieran, Radda, George K., Tyler, Damian J.
出版 2009

A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart

由 Cole, Mark A., Murray, Andrew J., Cochlin, Lowri E., Heather, Lisa C., McAleese, Sara, Knight, Nicholas S., Sutton, Elizabeth, Jamil, Amira Abd, Parassol, Nadege, Clarke, Kieran
出版 2011

Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart

由 Ashmore, Tom, Fernandez, Bernadette O, Branco-Price, Cristina, West, James A, Cowburn, Andrew S, Heather, Lisa C, Griffin, Julian L, Johnson, Randall S, Feelisch, Martin, Murray, Andrew J
發表在 J Physiol (2014)

Dimethyl-2-oxoglutarate improves redox balance and mitochondrial function in muscle pericytes of individuals with diabetes mellitus

由 Faulkner, Ashton, Tamiato, Anita, Cathery, William, Rampin, Andrea, Caravaggi, Carlo Maria, Jover, Eva, Allen, Steve, Mellor, Harry, Hauton, David, Heather, Lisa C., Spinetti, Gaia, Madeddu, Paolo
發表在 Diabetologia (2020)

L-Carnitine Stimulates In Vivo Carbohydrate Metabolism in the Type 1 Diabetic Heart as Demonstrated by Hyperpolarized MRI

由 Savic, Dragana, Ball, Vicky, Curtis, M. Kate, Sousa Fialho, Maria da Luz, Timm, Kerstin N., Hauton, David, West, James, Griffin, Julian, Heather, Lisa C., Tyler, Damian J.
發表在 Metabolites (2021)

Impaired In Vivo Mitochondrial Krebs Cycle Activity After Myocardial Infarction Assessed Using Hyperpolarized Magnetic Resonance Spectroscopy

由 Dodd, Michael S., Atherton, Helen J., Carr, Carolyn A., Stuckey, Daniel J., West, James A., Griffin, Julian L., Radda, George K., Clarke, Kieran, Heather, Lisa C., Tyler, Damian J.
發表在 Circ Cardiovasc Imaging (2014)

Validation of the In Vivo Assessment of Pyruvate Dehydrogenase Activity Using Hyperpolarized (13)C-Magnetic Resonance Spectroscopy

由 Atherton, Helen J., Schroeder, Marie A., Dodd, Michael S., Heather, Lisa C., Carter, Emma E., Cochlin, Lowri E., Nagel, Simon, Sibson, Nicola R., Radda, George K., Clarke, Kieran, Tyler, Damian J.
發表在 NMR Biomed (2010)

In Vivo Alterations in Cardiac Metabolism and Function in the Spontaneously Hypertensive Rat Heart

由 Dodd, Michael S., Ball, Daniel R., Schroeder, Marie A., Le Page, Lydia M., Atherton, Helen J., Heather, Lisa C., Seymour, Anne-Marie, Ashrafian, Houman, Watkins, Hugh, Clarke, Kieran, Tyler, Damian J.
發表在 Cardiovasc Res (2012)

Assessing the effect of hypoxia on cardiac metabolism using hyperpolarized (13)C magnetic resonance spectroscopy

由 Le Page, Lydia M., Rider, Oliver J., Lewis, Andrew J., Noden, Victoria, Kerr, Matthew, Giles, Lucia, Ambrose, Lucy J.A., Ball, Vicky, Mansor, Latt, Heather, Lisa C., Tyler, Damian J.
發表在 NMR Biomed (2019)

Rapid, [Formula: see text] ‐insensitive, dual‐band quasi‐adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux

由 Miller, Jack J., Valkovič, Ladislav, Kerr, Matthew, Timm, Kerstin N., Watson, William D., Lau, Justin Y. C., Tyler, Andrew, Rodgers, Christopher, Bottomley, Paul A., Heather, Lisa C., Tyler, Damian J.
發表在 Magn Reson Med (2021)