Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart

Hypoxic exposure is associated with impaired cardiac energetics in humans and altered mitochondrial function, with suppressed complex I-supported respiration, in rat heart. This response might limit reactive oxygen species generation, but at the cost of impaired electron transport chain (ETC) activi...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Ashmore, Tom, Fernandez, Bernadette O, Branco-Price, Cristina, West, James A, Cowburn, Andrew S, Heather, Lisa C, Griffin, Julian L, Johnson, Randall S, Feelisch, Martin, Murray, Andrew J
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253472/
https://ncbi.nlm.nih.gov/pubmed/25172947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.275263
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