Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism

BACKGROUND: Insulin sensitivity in skeletal muscle is associated with metabolic flexibility, including a high capacity to increase fatty acid (FA) oxidation in response to increased lipid supply. Lipid overload, however, can result in incomplete FA oxidation and accumulation of potentially harmful i...

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Udgivet i:BMC Biol
Main Authors: Ashmore, Tom, Roberts, Lee D., Morash, Andrea J., Kotwica, Aleksandra O., Finnerty, John, West, James A., Murfitt, Steven A., Fernandez, Bernadette O., Branco, Cristina, Cowburn, Andrew S., Clarke, Kieran, Johnson, Randall S., Feelisch, Martin, Griffin, Julian L., Murray, Andrew J.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688964/
https://ncbi.nlm.nih.gov/pubmed/26694920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0221-6
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