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Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism

BACKGROUND: Insulin sensitivity in skeletal muscle is associated with metabolic flexibility, including a high capacity to increase fatty acid (FA) oxidation in response to increased lipid supply. Lipid overload, however, can result in incomplete FA oxidation and accumulation of potentially harmful i...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Ashmore, Tom, Roberts, Lee D., Morash, Andrea J., Kotwica, Aleksandra O., Finnerty, John, West, James A., Murfitt, Steven A., Fernandez, Bernadette O., Branco, Cristina, Cowburn, Andrew S., Clarke, Kieran, Johnson, Randall S., Feelisch, Martin, Griffin, Julian L., Murray, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688964/
https://ncbi.nlm.nih.gov/pubmed/26694920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0221-6
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