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Changes in Cardiac Substrate Transporters and Metabolic Proteins Mirror the Metabolic Shift in Patients with Aortic Stenosis

In the hypertrophied human heart, fatty acid metabolism is decreased and glucose utilisation is increased. We hypothesized that the sarcolemmal and mitochondrial proteins involved in these key metabolic pathways would mirror these changes, providing a mechanism to account for the modified metabolic...

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Main Authors: Heather, Lisa C., Howell, Neil J., Emmanuel, Yaso, Cole, Mark A., Frenneaux, Michael P., Pagano, Domenico, Clarke, Kieran
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196577/
https://ncbi.nlm.nih.gov/pubmed/22028857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026326
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