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Mechanism of formate–nitrite transporters by dielectric shift of substrate acidity

Bacterial formate–nitrite transporters (FNTs) regulate the metabolic flow of small, weak mono‐acids. Recently, the eukaryotic PfFNT was identified as the malaria parasite's lactate transporter and novel drug target. Despite crystal data, central mechanisms of FNT gating and transport remained u...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Wiechert, Marie, Beitz, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376963/
https://ncbi.nlm.nih.gov/pubmed/28250043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695776
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