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Mechanism of formate–nitrite transporters by dielectric shift of substrate acidity
Bacterial formate–nitrite transporters (FNTs) regulate the metabolic flow of small, weak mono‐acids. Recently, the eukaryotic PfFNT was identified as the malaria parasite's lactate transporter and novel drug target. Despite crystal data, central mechanisms of FNT gating and transport remained u...
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| Published in: | EMBO J |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
John Wiley and Sons Inc.
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5376963/ https://ncbi.nlm.nih.gov/pubmed/28250043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695776 |
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