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TITIN ISOFORM EXPRESSION IN AORTIC STENOSIS

BACKGROUND: Titin is a giant sarcomeric protein that plays a major role in determining passive myocardial stiffness. The shorter N2B isoform results in a higher passive myocardial stiffness than the longer N2BA isoform. We hypothesised that expression of the short N2B isoform would be increased in p...

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Detalhes bibliográficos
Main Authors: Williams, Lynne, Howell, Neil, Pagano, Domenico, Andreka, Peter, Vertesaljai, Marton, Pecor, Tiffany, Frenneaux, Michael, Granzier, Henk
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419140/
https://ncbi.nlm.nih.gov/pubmed/19154184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20080248
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