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Titin isoform variance and length dependence of activation in skinned bovine cardiac muscle

We have explored the role of the giant elastic protein titin in the Frank-Starling mechanism of the heart by measuring the sarcomere length (SL) dependence of activation in skinned cardiac muscles with different titin-based passive stiffness characteristics. We studied muscle from the bovine left ve...

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Autores principales: Fukuda, Norio, Wu, Yiming, Farman, Gerrie, Irving, Thomas C, Granzier, Henk
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2343481/
https://ncbi.nlm.nih.gov/pubmed/12963792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.049759
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