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Troponin and Titin Coordinately Regulate Length-dependent Activation in Skinned Porcine Ventricular Muscle
We investigated the molecular mechanism by which troponin (Tn) regulates the Frank-Starling mechanism of the heart. Quasi-complete reconstitution of thin filaments with rabbit fast skeletal Tn (sTn) attenuated length-dependent activation in skinned porcine left ventricular muscle, to a magnitude sim...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2248715/ https://ncbi.nlm.nih.gov/pubmed/18299397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709895 |
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