Protein kinase A–dependent modulation of Ca(2+) sensitivity in cardiac and fast skeletal muscles after reconstitution with cardiac troponin

Protein kinase A (PKA)-dependent phosphorylation of troponin (Tn)I represents a major physiological mechanism during β-adrenergic stimulation in myocardium for the reduction of myofibrillar Ca(2+) sensitivity via weakening of the interaction with TnC. By taking advantage of thin filament reconstitut...

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Detalhes bibliográficos
Main Authors: Matsuba, Douchi, Terui, Takako, O-Uchi, Jin, Tanaka, Hiroyuki, Ojima, Takao, Ohtsuki, Iwao, Ishiwata, Shin'ichi, Kurihara, Satoshi, Fukuda, Norio
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713144/
https://ncbi.nlm.nih.gov/pubmed/19433622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910206
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