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Regulatory mechanism of length-dependent activation in skinned porcine ventricular muscle: role of thin filament cooperative activation in the Frank-Starling relation

Cardiac sarcomeres produce greater active force in response to stretch, forming the basis of the Frank-Starling mechanism of the heart. The purpose of this study was to provide the systematic understanding of length-dependent activation by investigating experimentally and mathematically how the thin...

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Главные авторы: Terui, Takako, Shimamoto, Yuta, Yamane, Mitsunori, Kobirumaki, Fuyu, Ohtsuki, Iwao, Ishiwata, Shin’ichi, Kurihara, Satoshi, Fukuda, Norio
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947055/
https://ncbi.nlm.nih.gov/pubmed/20876361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010502
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